It's been a while since I posted about my son "Jake". For those who haven't read his story, here is the link http://www.fecalmicrobiotatransplant.com/2013/07/crohns-disease-fmt.html . He has been off medication (Imuran) for nine months now and looks and feels well. Unfortunately his cousin who was his donor became unsuitable to donate in mid August due to picking up a parasite, so Jake has gone since then without any FMT.
Today he had a colonoscopy and endoscopy and we were thrilled with the news. There is no sign of Crohn's Disease anywhere - not in his intestines, not in his terminal ileum and not in his duodenum!!! In fact, Professor Borody said there was no scarring or ulceration or any indication that the disease had ever existed. It was all perfect, healthy and inflammation-free. When he was first diagnosed with Crohn's three years ago it was very widespread. I am sure that anyone reading who has any experience or understanding of Crohn's Disease will appreciate just how incredible this is! The persistence has paid off.
It's still too early to say that this is a cure - only time will tell that, but his remission is not just clinical, it's visible and histological remission with no medication. This has completely defied the "odds" so far. It's the miracle we prayed for and it is Jake's wish and mine that this will give hope to others with this terrible disease.
I am one very, very happy mother! What an absolute "legend" of a doctor Professor Borody is!!
Oh and by the way, Jake's skin is still clear - his acne never returned :-)
Wonderful to read! My son is suffering from Chrons since 11 years back. I don´t know if FMT could help him because he has removed his colon... Do you know anything about that? All the best for you and your son!
ReplyDeleteI tried to search in Google Scholar to see if there were any medical papers on that for your son, but I couldn't find anything as yet. I have no idea if FMT is viable when a colon has been removed and it's an interesting question. Don't give up on the idea, FMT is rapidly evolving so there may be some case studies or small studies done in time. A good place to look for up to date information is http://scholar.google.com - new medical papers come up all the time. I wish you and your son the very best also!
DeleteThank you so much for your information! All the best!
DeleteJake's story gives me the hope and inspiration in my own fight with crohns.. Thanks for sharing it. You are an incredible mother and Jake is very lucky to have you. I hope your son his cured of crohn's forever so he can have a normal life.
ReplyDeleteThank you! I am so happy to know that Jake's success so far has given you hope - we all need to know there is hope for a cure for Crohn's Disease - sometimes, hope is all we have! From the bottom of our hearts, Jake and I wish you the cure you deserve. :-)
DeleteMy son was diagnosed with Crohn's when he was 12 years old. He will be 18 this summer. We have tried everything, and I mean everything......holistic and pharma. I really want to get this for him. Any advice on how to find a dr in our area? If not in our area, the closest possible? We live in Louisiana. He was recently tested positive for cdiff too but when I asked the drs at childrens about doing it, they looked at me as if I had 2 heads!
ReplyDeletePlease feel free to email me: breanie5157@charter.net
Any info would be greatly appreciated!
PS.....So happy for you and your son! :)
Hi Sir
ReplyDeleteCan I know from Jack father how inflammation and ulceration of duodenum and ileum treated while the fecal solution reached only to the colon only?? because there is a valve in the end of colon prevent solution to go to ileum and other
parts of digestive tract.
Kind Regards
The first time "Jake" was infused with FMT was via colonoscope which reached all the way to the terminal ileum. After that, all the FMT treatments were done as rectal infusions. Your question is very interesting! Professor Borody himself has pondered in amazement how the ulceration in his duodenum reversed after FMT, and one can only hypothesise on this at present.... he believes that my son's Crohn's disease began in the terminal ileum which is quite common and spread to the other areas - his terminal ileium was the worst affected area, followed by the duodenum. Just as the disease itself spread to other areas of his digestive system, so did the benefits of FMT which appeared to have killed off the infection which was causing Crohn's. It's Professor Borody's belief (and a growing and somewhat controversial belief among gastroenterologists) that Crohn's Disease is caused by infection by various pathogens, the most common of which is Paratuberculosis which causes Johnes disease in cattle. I hope this helps answer your question somewhat - it's been very exciting to see the reversal of such an insidious disease, and know that we are a part of something that could completely change the lives others with Crohn's.
DeleteHi,
DeleteIm 29 yr female frm india and suffering frm chrone since 2007
I'm on imuran since 2008 and also taking steroids course once or sometime twice a year when the disease got active.
but from last 10 months im getting blood n mucus frm stool and tried all the
medications but nothing help with it
my dr said that I'm having severe activity in my rectum n sigmoid colon and for that I tried many different enemas include prednisone enema also but 0 result
im hospitalised now n today my dr told me about FMT and while search I found ur webpage.
dr have done capsule endoscopy for which the report will cum tomorrow and dr told me that if I have more ulcers in my small intestine then he is going to give me imuran injection also called " infleximab" with FMT
Did dr borody also gave imuran injection to jade with his first FMT ?
What is the test called of donor stool ?
please I would to talk with the author of this post, please have them contact me.
ReplyDeletemy contact information are :mislamy15m@gmail.com
720-737-0542
I still need the answer and other information by contact me on my email and my phone please : mislamy15m@gmail.com-------------720-737-0542
ReplyDeleteI live in Australia and my son sees Professor Borody at http://www.cdd.com.au in Sydney. Unfortunately the FDA in the USA has placed restrictions on Fecal Transplant use for anything other than severe cases of C-difficile. There is a website at http://www.thepowerofpoop.com which has more pertinent and up-to-date information to help someone than I can offer. I wish I could help you more but do not have the resources. I wish you the very best treatment, care and recovery.
DeleteThank you Admin For your information that let me contact with Jack Mom and your honest feeling about me.
DeleteYou're very welcome! :-)
DeleteI am 27 and I have been diagnosed with Crohn's since 2009. At first it was only in my colon and now it has moved into my small intestine. I was first put on Remicade which worked great for a little over 2 years then started causing severe joint pain that was attributed to my body building up antibodies to the Remicade. I eventually had an allergic reaction to it and was switched to Humira. The Humira worked great for a little over 2 years until now, I had to be hospitalized twice due to a flare up (my first flare up since being diagnosed in 2009 - Crohn's was in remission up until now). This is due to the fact that my body is now building up antibodies to the Humira. My doctor fearing running out of treatment option so instead of taking me off the Humira, he has decided to add the drug 6-MP. So far so good, but would be much happier with something like FMT and getting off these harsh medications. I have also developed psoriasis this past year. Just seems too much of a coincidence that I developed arthritis with the Remicade and now psorasis with the Humira. I guess my question is, is it possible to have FMT treatments supervised by a doctor without having C-diff and if not, how do you get a suitable donor to DIY at home?
ReplyDeleteDoes anyone know of FMT donor screening activity in the Wellington NZ area? The FMT enema-infusion performed DIY appears to be low risk. But the donor screening requires lab tests which cannot be ordered DIY. Thanks for any information.
ReplyDeleteIt's great News! Good luck and stay blessed. Our 8 yrs old son was diagnosed with UC when he was 6.5yrs old. FMT puts some rays of hope on IBD. We stay in Sydney, Australia. Can we connect sometime please so we can benefit with the information to heal my son. Here is my mail id - priya.desai@gmail.com
ReplyDeleteThanks & regards,
Priya